Investigator
University of Cape Town
Cape Town, Western Cape
6d ago
source : Best Za Jobs

The Drug Discovery and Development Centre (H3D) is an interdisciplinary, soft-funded research unit at the University of Cape Town.

H3D staff and laboratories are situated across three sites on the UCT campus. H3D is seeking to appoint an Investigator on a 2-year contract, starting on 1 August 2021 or as soon as possible thereafter.

This position will be predominantly laboratory-based with the main purpose in taking a leading role in the synthesis of novel compounds to optimize drug-like properties on drug discovery projects.

Requirements : PhD in an appropriate discipline or equivalent qualification 2 or more years industrial or academic experience in a drug discovery or related research laboratory A track record of publications in medicinal chemistry and / or organic chemistry journals with major contributions to compound synthesis Up to date on laboratory technologies and strong bench experience in synthetic organic chemistry and characterisation of organic compounds Comfortable working in a matrix-based organizational structure Advantages : Experience in a drug discovery team either in a university setting or at a pharmaceutical / biotech company Demonstrated ability to use structure-activity relationships and other medicinal chemistry practices to aid optimization of hit to lead and lead to preclinical candidate Proficiency in the use of all equipment in a modern chemistry laboratory including parallel synthesis, automated purifications techniques Responsibilities will include, but are not limited to the following : Independently synthesize compounds within a team setting with the goal to identify pre-clinical drug candidates.

Use structure-activity relationships and other medicinal chemistry practices to aid optimization of hit to lead and lead to preclinical candidate Comply with standard operating procedures for laboratory safety, use of instruments and data management.

Participate and present work in project meetings and write research reports Interested candidates can send their CV To apply, please e-mail the below documents in a single pdf file to Ms Alacia Armstrong : - UCT Application Form (download at http : / / forms.

uct.ac.za / hr201.doc) - Cover letter stating your suitability for the role - Curriculum Vitae (CV)

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